Biography:
Currently a student in the Computation and Neural Systems program at the California Institute of Technology, Saanvi combines computational modeling with developmental neuroscience. Previously, at the Seattle Children's Research Institute, she utilized topic modeling frameworks on large-scale genomic atlases to reconstruct the lineage of the cerebellar rhombic lip. Her work focused on characterizing the transient progenitor states that are co-opted in Sonic Hedgehog medulloblastoma subtypes.
Title : Elucidating neurodevelopmental trajectories in cancer with topic modeling: Revealing persistent external granule layer lineages in medulloblastoma