Biography:
Arpit Ramani is a 12th-grade student at Wheeler Magnet High School. For the past four years, he has conducted independent research on Alzheimer’s disease drug development, creating computational pipelines to model and evaluate therapeutic candidates. He also conducts research at Emory University using statistical genetics to identify biomarkers for Alzheimer’s disease. Arpit’s most recent work was done through the BU RISE program, in which he expanded his research by applying neuronal modeling to study brain health. Arpit hopes that his current efforts in Alzheimer’s disease research will serve as a foundation for his future pursuit of medicine and neurodegenerative drug development.
Title : A multiscale systems biology framework integrating ODE-based kinetics and MD-derived structural affinities to model mBDNF–proBDNF-mediated bifurcation dynamics in CNS neurotrophin signaling